admin – Page 5 – Chemical Crystallography Research Laboratory

Supramolecular Interactions in the Solid State

15/08/201510/08/2017 admin

Giuseppe Resnati, Elena Boldyreva, Petra Bombicz, Masaki Kawano IUCrJ, 2, 675-690 (2015) Abstract In the last few decades, supramolecular chemistry has been at the forefront of chemical research, with the aim of understanding chemistry beyond the covalent bond. Since the long-range periodicity in crystals is a product of the directionally specific short-range intermolecular interactions that are responsible for molecular assembly, analysis of crystalline solids provides a primary means to investigate intermolecular interactions and recognition phenomena. This article discusses some areas Read More …

Tamás Holczbauer won the Academic Research Prize for Young Scientist

09/08/201510/08/2017 admin

His proposal titled “Development of crystallization processes to establish solid state molecular associations” was awarded by the Hungarian Academy of Sciences. Congratulations Tamás! See at the webpage of the Hungarian Academy of Sciences

Vanadium(IV/V) complexes of Triapine and related thiosemicarbazones: Synthesis, solution equilibrium and bioactivity

21/06/201506/09/2017 admin

Kowol CR, Nagy NV, Jakusch T, Roller A, Heffeter P, Keppler BK, Enyedy ÉA Journal of Inorganic Biochemistry 152 (2015) 62–73 Abstract The stoichiometry and thermodynamic stability of vanadium(IV/V) complexes of Triapine and two related α(N)-heterocyclic thiosemicarbazones (TSCs) with potential antitumor activity have been determined by pH-potentiometry, EPR and 51V NMR spectroscopy in 30% (w/w) dimethyl sulfoxide/water solvent mixtures. In all cases, mono-ligand complexes in different protonation states were identified. Dimethylation of the terminal amino group resulted in the formation of Read More …

Fine tuning of crystal architecture by intermolecular interactions: synthon engineering

09/08/201406/09/2017 admin

Petra Bombicz, Tobias Gruber, Conrad Fischer, Edwin Weber, Alajos Kálmán CrystEngComm, 16 (18), 3646 – 3654, 2014 Abstract There has been a long time effort to influence or favourably fine tune structural properties by introduction of substituents or guest molecules of different sizes, shapes and chemical composition to consequently alter physico-chemical properties of the respective crystals. These attempts require the recognition, understanding and application of intermolecular interactions, crystallographic and, in case of occurrence, non-crystallographic symmetries. It brings us to the Read More …